Population Genetics and Molecular Evolution
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The use of recombinant DNA technology and DNA sequencing allows variability within species and evolutionary change to be studied at the most fundamental level. New insights into the organization and evolution of the genome, the impact of selection on DNA and protein sequences, and the history of life, are emerging as a result. The generation and interpretation of the relevant data requires integration of knowledge from molecular biology, evolutionary biology, population genetics, statistics, and bioinformatics. The purpose of the school is to give an introduction to some of the current problems and approaches in this rapidly changing field.
Program
| Monday, April 9: | |
|---|---|
| 9.00 | Opening of the Spring School |
| 9.15 - 10.45 | Brian Charlesworth, University of Edinburgh "The analysis of intraspecific DNA sequence variation" |
| 11.15 - 12.45 | Wen-Hsiung Li, University of Chicago "Human DNA polymorphism and evolution" |
| 15.15 - 16.45 | Adam Eyre-Walker, University of Sussex "Estimating the rates and fitness effects of genetic mutations" |
| 18.00 | Reception and Buffet Diner |
| Tuesday, April 10: | |
| 9.15 - 10.45 | Adam Eyre-Walker, University of Sussex "The evolution of synonymous codon bias and genome structure" |
| 11.15 - 12.45 | Wen-Hsiung Li, University of Chicago "Male-driven evolution in mammals and birds" |
| 15.15 - 16.45 | Brian Charlesworth, University of Edinburgh "The effect of genomic location on molecular evolution" |
| Public Lecture | |
| 18:15 | Deborah Charlesworth, University of Edinburgh "Genome sequences and evolutionary biology" |
| Wednesday, April 11: | |
| 9.15 - 10.45 | Wen-Hsiung Li, University of Chicago "Evolution of visual pigment genes" |
| 11.15 - 12.45 | Brian Charlesworth, University of Edinburgh "The population dynamics of transposable elements" |
| 14.15 - 15.45 | Adam Eyre-Walker, University of Sussex "The evidence for recombination in mitochondrial DNA" |
Location:
| Room: | Lecture Hall 12 |
| Building: | Institute for Biology |
| Street: | Invalidenstraße 43 |
| ZIP Code: | 10115 |
| City: | Berlin |
Registration
For registration, send an e-mail with your name and address or a letter to Innovationskolleg Theoretische Biologie, Humboldt-Universität zu Berlin, Invalidenstraße 43, 10115 Berlin, Tel.: 030-2093-9112, Fax: 030-2093-8801 before March 15. The registration fee of 50 DM (to be paid upon arrival) includes the buffet on April 9. The registration fee for students is 25 DM.
Publications
Wen-Hsiung Li, 1997: Molecular Evolution. Sinauer Associates, Inc., Publishers , Marshall, Mark, S.; 1995: RAS target proteins in eukaryotic cells. In: FASEB Vol. 9, October 1995 pp.1311-1318 Schäfer, R.; 1994: Suppression of RAS Oncogene-Mediated Transformation. In: Rev. Physiol. Biochem. Pharmacol., Vol. 124, pp.30-91 Tschernitsa, Oleg et al.; 1999: Gene expression profiling of fibroblasts ... In: Oncogene Vol. 18, pp. 5448-5454