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SS 2005

Computational Neuroscience: Oberseminar (31197)

Dr. Laurenz Wiskott, Prof. Andreas V. M. Herz, and Dr. Richard Kempter
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Oberseminar: Monday 11-13 Uhr in the ITB seminar room (Invalidenstraße 43)

In this seminar various topics of current research in computational neuroscience are presented. Attendees should have basic knowledge in neuroscience and computational neuroscience, e.g. from the courses "Computational Neuroscience I-IV".



04.04.2005 Marion Moisel
"Simultaneous recording of postsynaptic field potentials with transistor chips in hippocampal brain slices"

Abstract: Different arrays of small transistors were placed in hippcampal CA1 and CA3 region to measure profiles of evoked field potentials with high spatial resolution of several micrometers. Schaffer collaterals or mossy fibers were stimulated, respectively. Sharp positive and negative peaks in the transistor records mark up and downward steps of the voltage pulse. They are due to the spread of the capacitive current through the slice and bath to the position of recording. The method is valid for investigation of long-term potentiation. Linear array are suitable for studies along and across the strata.

Literature:
B. Besl and P. Fromherz (2002):"Transistor array with an organotypic brain slice: field potential records and synaptic currents" European Journal of Neuroscience, Vol. 15, pages 999-1005
M. Hutzler and P. Fromherz (2004): "Silicon chip with capacitors and transistors for interfacing organotypic brain slice of rat hippocampus", European Journal of Neuroscience, Vol. 19, pages 2231-2238

11.04.2005 Roland Schätte
"Homeostatic Plasticity"

Abstract: Short review of some basic papers, overview over mechanisms and possible purposes of homeostatic plasticity.

18.04.2005 Idan Segev (Hebrew University)
"What can we learn from a detailed model of a cortical column? The first steps"

25.04.2005 Martin Stemmler

02.05.2005 Christian Leibold and Laurenz Wiskott
"Impressions from the Cosyne Meeting"

09.05.2005 Lars Schwabe (Technische Universität Berlin, Fakultät IV - Elektrotechnik und Informatik)
"Adaptivity of tuning functions and top-down modulation in circuit models of the visual cortex"

Abstract: Orientation tuning functions in the visual cortex are highly adaptive. They are changed by the spatial, temporal, and behavioral context. In this talk I first consider the adaptivity of tuning functions in the visual cortex as observed in attention and perceptual learning experiments from the perspective of optimally encoding sensory information. Using a recurrent network model of an orientation hypercolumn I demonstrate that the two phenomena 'perceptual learning' and 'attention' can be viewed as dynamic recalibrations of sensory representations which operate on different time-scales and via different mechanisms.
One possible mechanisms to rapidly adjust tuning function is via top-down modulation of neuronal activity. The concrete circuits underlying these top-down modulations, however, are still not completely known. In other words, physiologically plausible mechanistic circuit models for these top-down modulations are needed.
Therefore, in the second part of my talk I will present a network model of contextual effects in primary visual cortex, which includes top-down feedback. The model is compatible with a large set of experimental data, and it makes specific predictions for new experiments. Thus, this model can used to further constrain the mechanistic circuit models of the modulatory effects presented in the first part of my talk.

23.05.2005 Henning Sprekeler
"SFA Yields Complex Cells: Theoretical Analysis"

30.05.2005 Michael Bendels
"Synchronisation of pulse coupled Neurons"

06.06.2005 Tim Oppermann

13.06.2005 Raphael Ritz
"Update on our web development activities"


20.06.2005 Felix Creutzig
"The Dynamical System Information Bottleneck"


27.06.2005 Alexander Wolf
"Discrimination between Nonlinearities in the Mechanosensory-Transduction Chain of the Locust Auditory System: Experimental Results"


04.07.2005 Christian Leibold
How to Couple Oscillators (?) A Network Theory of Synchronization Despite Noise


11.07.2005 Samuel Glauser
"Resonance effect for neural spike time reliability"


18.07.2005 Pietro Berkes
Risks and benefits of an open-source science: is it possible to make research freely available?


Abstract: Since I am leaving the ITB in two weeks, I would like to use this last opportunity to benefit from your know-how. I am going to present an overview of risks and benefits of making the data and software concerning a paper or an entire research project freely available. Moreover, I am going to discuss some steps that can be taken to make the results reproducible and to minimize errors. In this field there are a lot of open questions but only few anwers and there is little discussion going on. Since many of you have some experience here (e.g., the OEL people) I would like to hear about your solutions and problems.

25.07.2005 Tim Gollisch (Dept. of Molecular and Cellular Biology, Harvard University)
"Estimating receptive fields in the presence of spike-time jitter"

05.09.2005 Jan Benda
"Two Coding Strategies for Communication Signals in a Population Rate Code"


12.09.2005 Horacio G. Rotstein
"Canard structures and subthreshold oscillations in single neuron models"


Abstract: Medial entorhinal cortex layer II stellate cells display complex mixed-mode oscillatory (MMO) patterns in which both subthreshold oscillations (STOs) and spikes coexist. We study a biophysical model of such cells which qualitatively reproduces this MMO activity. We show that, during the interspike interval (ISI) where STOs are generated, this seven-dimensional model can be reduced to a three-dimensional one, with two well differentiated time scales. Using dynamical systems arguments we provide a mechanism for generations of STOs. This mechanism is based on a "canard structure", in which relevant trajectories stay close to repelling manifolds for a significant interval of time. We also show that the transition from subthreshold oscillatory activity to spiking ("canard explosion") is controlled in the ISI by the same structure. A similar mechanism is invoked to explain why noise increases the robustness of the STO regime.

19.09.2005 Mathias Franzius
"SFA for Placefield Modelling"


26.09.2005 Merav Ahissar (The Hebrew University of Jerusalem, Department of Psychology and Center for Neural Computation, Jerusalem, Israel)
"Reverse Hierarchy Theory and Dyslexia"


Created by Laurenz Wiskott, http://itb.biologie.hu-berlin.de/~wiskott/