==== Welcome to the group of Hanspeter Herzel ==== The group was established within the Institute for Theoretical Biology (ITB) in 1996 and belongs to the Charité and the Humboldt University Berlin. We apply methods from dynamical systems, data analysis and bioinformatics to address biomedical questions. Examples are voice production, heart dynamics, DNA periodicities, gene regulation, and circadian rhythms. ==== Theoretical Chronobiology ==== Together with the experimental groups of Achim Kramer (Charité), Michael Brunner (Heidelberg), Erik Herzog (St. Luis) and Toru Takumi (Tokyo) we investigate the generation and synchronization of circadian rhythms on different levels: - Modeling intracellular **feedback regulation** in the core clock oscillator - Studying the entrainment, **synchronization** and splitting of SCN neurons - Bioinformatic analysis (high-throughput data, promoter studies, epigenetics) of phase- and tissue specificity of **clock-controlled genes** - **Entrainment phase** control based on oscillator theory ==== Teaching Activities in Quantitative Biology ==== The group is involved in the education of students in biology, biophysics and molecular medicine. Together with colleagues from the ITB we teach regularly: * Mathematics for Biologists * Biostatistics * Modeling in Quantitative Biology * Bioinformatics * Functional Genomics ==== Network Activities ==== We are involved in several overarching consortia: * IRI - Integrative Research Institute for the Life Sciences * CSB - Graduate School Computational Systems Biology * TRR 186 - Molecular Switches * CompCancer - Graduate School Computational Oncology * Mind & Brain Graduate School * BSIO - Berlin School for Integrative Oncology ==== Contact and Publications ==== Prof. Dr. Hanspeter Herzel Institute for Theoretical Biology Philippstr. 13 D-10115 Berlin Tel. +30 2093 98402 Fax +30 2093 8801 E-mail: h.herzel[at]biologie.hu-berlin.de or hans-peter.herzel[at]charite.de Most recent publications can be seen via Pubmed (Herzel H). Most papers are freely available via Google Scholar or Research Gate. A complete list of publications as pdf-file: {{:members:herzel:pub.pdf|Publication list in *.pdf format}}\\