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| - | ====== Junior Group Systems Biology of Liver ====== | + | |
| - | {{: | + | ====== Systems Medicine of Liver ====== |
| - | Institute for Theoretical Biology\\ | ||
| - | Humboldt-University Berlin\\ | ||
| - | Invalidenstraße 43, 10117 Berlin, Germany\\ | ||
| - | phone +49 30 2093-8450\\ | ||
| - | [[konigmatt@googlemail.com ]] | ||
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| - | We are investigating liver metabolism and function with the help of computational models and methods.\\ | ||
| - | Read more about the group: [[https:// | ||
| - | [[https:// | ||
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| - | The liver is the central metabolic organ of our body playing a crucial role in the clearance of | ||
| - | drugs, xenobiotics and numerous metabolites from the bloodstream. The quantification of these | ||
| - | liver functions is essential to assess the status of the liver, obtain information about the degree | ||
| - | of impairment, to evaluate treatment response or to select transplant recipients. | ||
| - | This project will establish a standardized multiscale model framework of the human liver readily | + | {{: |
| - | adaptable to various quantitative liver function tests currently used in the clinics. The resulting | + | |
| - | models will be personalized with individual imaging data from CT and PET in combination with | + | **Group Leader**\\ |
| - | anthropomorphic information like gender, age, body weight and height and used for the | + | [[https:// |
| - | evaluation of quantitative liver function tests in a personalized context. Within this project three | + | |
| - | main applications will be realized, respectively represented by a showcase | + | Humboldt-University Berlin\\ |
| - | - normal liver function (galactose) | + | Institute for Biology, Institute for Theoretical Biology\\ |
| - | - detoxification of drugs (drug cocktail, indocyanine green, bromsulphalein) | + | Philippstraße 13, 10115 Berlin, Germany\\ |
| - | - impaired liver (cirrhosis & liver disease) | + | phone +49 30 2093 98435\\ |
| - | \\ | + | **[[koenigmx@hu-berlin.de]]**\\ |
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