The research group ''Theoretical Neuroscience'' is interested in the neural basis of learning and memory. Research involves the biophysical modeling and mathematical analysis of synapses, neurons, and neural systems. Theoretical approaches and computer simulations are used to study synaptic short- and long-term plasticity, the dynamics of single neurons, and the interaction of neurons in recurrently coupled networks. I am particularly fascinated by mechanisms that control the development and functional stability of neural circuits. One of my key goals is to unravel how such systems remain susceptible to learning, and, at the same time, maintain a robust balance against instabilities. Understanding the mechanisms that prevent neural tissue from developing pathological activity patterns will also help to uncover origins of functional brain illnesses and lead to practical implications for designing remedial therapies. Model systems are the hippocampus and the early auditory system.