Prof. Dr. Hanspeter Herzel
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Welcome to the group of Hanspeter Herzel
The group was established within the Institute for Theoretical Biology (ITB) in 1996 and belongs to the Charité and the Humboldt University Berlin. We apply methods from dynamical systems, data analysis and bioinformatics to address biomedical questions. Examples are voice production, heart dynamics, DNA periodicities, gene regulation, T-cell differentiation and circadian rhythms.
Theoretical Chronobiology
Together with the experimental group of Achim Kramer (Charité) we investigate the generation and synchronization of circadian rhythms on different levels:
- Modeling intracellular feedback regulation in the core clock oscillator
- Studying the entrainment, synchronization and splitting of SCN neurons
- Bioinformatic analysis (high-throughput data, promoter studies, epigenetics) of phase- and tissue specificity of clock-controlled genes
- Entrainment phase control based on oscillator theory
Teaching Activities in Quantitative Biology
The group is involved in the education of students in biology, biophysics and molecular medicine. Together with colleagues from the ITB we teach regularly:
- Mathematics for Biologists
- Biostatistics
- Modeling in Quantitative Biology
- Bioinformatics
- Functional Genomics
Systems Biology of the Circadian Clock
Together with the experimental group of Achim Cramer (Charité) we investigate the generation and synchronization of circadian rhythms on three different levels:
- Modeling intracellular feedback regulation in the core clock oscillator
- Studying the entrainment, synchronization and splitting of SCN neurons
- Bioinformatic analysis (high-throughput data, promoter studies, epigenetics) of phase- and tissue specificity of clock-controlled genes
Publications
Old Link!!! List of H. Herzel's Publications in *.pdf format