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groups:steuer:research [2016/12/09 16:50] – [Understanding Phototrophic Growth] steuergroups:steuer:research [2017/08/12 13:39] – [Understanding Phototrophic Growth] steuer
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 **Further reading:**  **Further reading:** 
-  * Ruegen M, Bockmayr A, Steuer R.  (2015) **[[http://www.ncbi.nlm.nih.gov/pubmed/26496972|Elucidating temporal resource allocation and diurnal dynamics in phototrophic metabolism using conditional FBA]]** Sci Rep. 5:15247. doi: 10.1038/srep15247. +  * Westermark S and Steuer R (2016) **[[http://journal.frontiersin.org/article/10.3389/fbioe.2016.00095/|Toward Multiscale Models of Cyanobacterial Growth: A Modular Approach.]]** Front. Bioeng. Biotechnol. 4:95. doi: 10.3389/fbioe.2016.00095 
-  * H. Knoop, M. Gruendel, Y. Zilliges, R. Lehmann, S. Hoffmann, W. Lockau, R. Steuer. (2013) **[[http://www.ncbi.nlm.nih.gov/pubmed/23843751|Flux Balance Analysis of Cyanobacterial Metabolism: The metabolic network of Synechocystis sp. PCC 6803.]]** PLoS Comput Biol 9(6): e1003081. doi:10.1371/journal.pcbi.1003081 +  * Reimers AM, Knoop H, Bockmayr A, Steuer R.​ (2017) **[[https://www.ncbi.nlm.nih.gov/pubmed/28720699|Cellular trade-offs and optimal resource allocation during cyanobacterial diurnal growth.]]** Proc Natl Acad Sci U S A. pii: 201617508. doi: 10.1073/pnas.1617508114. 
-  * R. Steuer, H. Knoop, R. Machne (2012) **[[http://www.ncbi.nlm.nih.gov/pubmed/22450165|Modelling cyanobacteria: from metabolism to integrative models of phototrophic growth.]]** Journal of Experimental Botany 63(6):2259-74. doi:10.1093/jxb/ers018 \\+  * H. Knoop, M. Gruendel, Y. Zilliges, R. Lehmann, S. Hoffmann, W. Lockau, R. Steuer. (2013) **[[http://www.ncbi.nlm.nih.gov/pubmed/23843751|Flux Balance Analysis of Cyanobacterial Metabolism: The metabolic network of Synechocystis sp. PCC 6803.]]** PLoS Comput Biol 9(6): e1003081. doi:10.1371/journal.pcbi.1003081 \\
  
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 Cyanobacteria have attracted growing attention as potential host organisms for the production of valuable organic products. We develop computational methods to facilitate and enhance production of renewable bulk products using cyanobacteria. The aim is to integrate photosynthetic solar energy conversion and product formation, including engine-ready fuels, in a single biological process.  Cyanobacteria have attracted growing attention as potential host organisms for the production of valuable organic products. We develop computational methods to facilitate and enhance production of renewable bulk products using cyanobacteria. The aim is to integrate photosynthetic solar energy conversion and product formation, including engine-ready fuels, in a single biological process. 
 Past target products are ethanol (in collaboration with several academic and industrial partners, including Algenol Deutschland GmbH), as well as short chain (propane) and medium chain alkanes.  Past target products are ethanol (in collaboration with several academic and industrial partners, including Algenol Deutschland GmbH), as well as short chain (propane) and medium chain alkanes. 
-High-quality reconstructions of cyanobacterial metabolism are used to guide and support experimental efforts to increase and sustain product yield in cyanobacteria. +High-quality reconstructions of cyanobacterial metabolism are used to guide and support experimental efforts to increase and sustain product yield in cyanobacteria. The group participated in launching a start-up company to commercialize cultivation of cyanobacteria and microalgae at ultra-high densities ([[http://www.celldeg.com|www.celldeg.com]]).
  
 **Further reading:**  **Further reading:**