Computational Modelling in Medicine
Prof. Dr. Nils Blüthgen
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2014
Petzoldt Astrid G, Lee Yü-Hien, Khorramshahi Omid, Reynolds Eric, Plested Andrew J R, Herzel Hanspeter, Sigrist Stephan J, 2014, Gating Characteristics Control Glutamate Receptor Distribution and Trafficking In Vivo. Curr. Biol., , (full text)
Ananthasubramaniam Bharath, Herzel Hanspeter, 2014, Positive feedback promotes oscillations in negative feedback loops. PLoS ONE, 9, e104761 (full text)
Klinger Bertram, Blüthgen Nils, 2014, Consequences of feedback in signal transduction for targeted therapies. Biochem. Soc. Trans., 42, 770-5 (full text)
Lehmann Robert, Machné Rainer, Herzel Hanspeter, 2014, The structural code of cyanobacterial genomes. Nucleic Acids Res., 42, 8873-83 (full text)
Korenčič Anja, Košir Rok, Bordyugov Grigory, Lehmann Robert, Rozman Damjana, Herzel Hanspeter, 2014, Timing of circadian genes in mammalian tissues. Sci Rep, 4, 5782 (full text)
Reifenstein Eric, Stemmler Martin, Herz Andreas V M, Kempter Richard, Schreiber Susanne, 2014, Movement dependence and layer specificity of entorhinal phase precession in two-dimensional environments. PLoS ONE, 9, e100638 (full text)
Beck Christian, Hertel Stefanie, Rediger Anne, Lehmann Robert, Wiegard Anika, Kölsch Adrian, Heilmann Beate, Georg Jens, Hess Wolfgang R, Axmann Ilka M, 2014, Daily Expression Pattern of Protein-Encoding Genes and Small Noncoding RNAs in Synechocystis sp. Strain PCC 6803. Appl. Environ. Microbiol., 80, 5195-206 (full text)
Killig Monica, Friedrichs Birte, Meisig Johannes, Gentilini Chiara, Blüthgen Nils, Loddenkemper Christoph, Labopin Myriam, Basara Nadezda, Pfrepper Christian, Niederwieser Dietger W, Uharek Lutz, Romagnani Chiara, 2014, Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation. Eur. J. Immunol., , (full text)
Relógio Angela, Thomas Philippe, Medina-Pérez Paula, Reischl Silke, Bervoets Sander, Gloc Ewa, Riemer Pamela, Mang-Fatehi Shila, Maier Bert, Schäfer Reinhold, Leser Ulf, Herzel Hanspeter, Kramer Achim, Sers Christine, 2014, Ras-mediated deregulation of the circadian clock in cancer. PLoS Genet., 10, e1004338 (full text)
Jaramillo Jorge, Schmidt Robert, Kempter Richard, 2014, Modeling inheritance of phase precession in the hippocampal formation. J. Neurosci., 34, 7715-31 (full text)
Roemschied Frederic A, Eberhard Monika Jb, Schleimer Jan-Hendrik, Ronacher Bernhard, Schreiber Susanne, 2014, Cell-intrinsic mechanisms of temperature compensation in a grasshopper sensory receptor neuron. Elife, 3, e02078 (full text)
Telschow Arndt, Hilgenboecker Kirsten, Hammerstein Peter, Werren John H, 2014, Dobzhansky-muller and wolbachia-induced incompatibilities in a diploid genetic system. PLoS ONE, 9, e95488 (full text)
Ananthasubramaniam Bharath, Herzog Erik D, Herzel Hanspeter, 2014, Timing of neuropeptide coupling determines synchrony and entrainment in the mammalian circadian clock. PLoS Comput. Biol., 10, e1003565 (full text)
Guerreiro Ana C L, Benevento Marco, Lehmann Robert, van Breukelen Bas, Post Harm, Giansanti Piero, Maarten Altelaar A F, Axmann Ilka M, Heck Albert J R, 2014, Daily Rhythms in the Cyanobacterium Synechococcus elongatus Probed by High-resolution Mass Spectrometry-based Proteomics Reveals a Small Defined Set of Cyclic Proteins. Mol. Cell Proteomics, 13, 2042-55 (full text)
Zug Roman, Hammerstein Peter, 2014, Bad guys turned nice? A critical assessment of Wolbachia mutualisms in arthropod hosts. Biol Rev Camb Philos Soc, , (full text)
Schulz Edda G, Meisig Johannes, Nakamura Tomonori, Okamoto Ikuhiro, Sieber Anja, Picard Christel, Borensztein Maud, Saitou Mitinori, Blüthgen Nils, Heard Edith, 2014, The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network. Cell Stem Cell, 14, 203-16 (full text)
Snijder Joost, Burnley Rebecca J, Wiegard Anika, Melquiond Adrien S J, Bonvin Alexandre M J J, Axmann Ilka M, Heck Albert J R, 2014, Insight into cyanobacterial circadian timing from structural details of the KaiB-KaiC interaction. Proc. Natl. Acad. Sci. U.S.A., 111, 1379-84 (full text)
Werner Gijsbert D A, Strassmann Joan E, Ivens Aniek B F, Engelmoer Daniel J P, Verbruggen Erik, Queller David C, Noë Ronald, Johnson Nancy Collins, Hammerstein Peter, Kiers E Toby, 2014, Evolution of microbial markets. Proc. Natl. Acad. Sci. U.S.A., 111, 1237-44 (full text)
Gottstein Willi, Müller Stefan, Herzel Hanspeter, Steuer Ralf, 2014, Elucidating the adaptation and temporal coordination of metabolic pathways using in-silico evolution. BioSystems, 117, 68-76 (full text)
Axmann Ilka M, Hertel Stefanie, Wiegard Anika, Dörrich Anja K, Wilde Annegret, 2014, Diversity of KaiC-based timing systems in marine Cyanobacteria. Mar Genomics, 14, 3-16 (full text)
Müller Stefan, Regensburger Georg, Steuer Ralf, 2014, Enzyme allocation problems in kinetic metabolic networks: optimal solutions are elementary flux modes. J. Theor. Biol., 347, 182-90 (full text)
2013
Müller Stefan, Regensburger Georg, Steuer Ralf, 2014, Enzyme allocation problems in kinetic metabolic networks: optimal solutions are elementary flux modes. J. Theor. Biol., 347, 182-90 (full text)
Zhuchkova Ekaterina, Remme Michiel W H, Schreiber Susanne, 2013, Somatic versus dendritic resonance: differential filtering of inputs through non-uniform distributions of active conductances. PLoS ONE, 8, e78908 (full text)
Hertel Stefanie, Zoschke Reimo, Neumann Laura, Qu Yujiao, Axmann Ilka M, Schmitz-Linneweber Christian, 2013, Multiple checkpoints for the expression of the chloroplast-encoded splicing factor MatK. Plant Physiol., 163, 1686-98 (full text)
Hermey Guido, Mahlke Claudia, Gutzmann Jakob J, Schreiber Jörg, Blüthgen Nils, Kuhl Dietmar, 2013, Genome-wide profiling of the activity-dependent hippocampal transcriptome. PLoS ONE, 8, e76903 (full text)
Knoop Henning, Gründel Marianne, Zilliges Yvonne, Lehmann Robert, Hoffmann Sabrina, Lockau Wolfgang, Steuer Ralf, 2013, Flux balance analysis of cyanobacterial metabolism: the metabolic network of Synechocystis sp. PCC 6803. PLoS Comput. Biol., 9, e1003081 (full text)
Glatzer Timor, Killig Monica, Meisig Johannes, Ommert Isabelle, Luetke-Eversloh Merlin, Babic Marina, Paclik Daniela, Blüthgen Nils, Seidl Rainer, Seifarth Claudia, Gröne Jörn, Lenarz Minoo, Stölzel Katharina, Fugmann Dominik, Porgador Angel, Hauser Anja, Karlas Alexander, Romagnani Chiara, 2013, RORγt⁺ innate lymphoid cells acquire a proinflammatory program upon engagement of the activating receptor NKp44. Immunity, 38, 1223-35 (full text)
Bentele Kajetan, Saffert Paul, Rauscher Robert, Ignatova Zoya, Blüthgen Nils, 2013, Efficient translation initiation dictates codon usage at gene start. Mol. Syst. Biol., 9, 675 (full text)
Klinger Bertram, Sieber Anja, Fritsche-Guenther Raphaela, Witzel Franziska, Berry Leanne, Schumacher Dirk, Yan Yibing, Durek Pawel, Merchant Mark, Schäfer Reinhold, Sers Christine, Blüthgen Nils, 2013, Network quantification of EGFR signaling unveils potential for targeted combination therapy. Mol. Syst. Biol., 9, 673 (full text)
Carr Catherine, Shah Sahil, Ashida Go, McColgan Thomas, Wagner Hermann, Kuokkanen Paula T, Kempter Richard, Köppl Christine, 2013, Maps of ITD in the nucleus laminaris of the barn owl. Adv. Exp. Med. Biol., 787, 215-22 (full text)
Herbst Christian T, Herzel Hanspeter, Svec Jan G, Wyman Megan T, Fitch W Tecumseh, 2013, Visualization of system dynamics using phasegrams. J R Soc Interface, 10, 20130288 (full text)
Lehmann Robert, Machné Rainer, Georg Jens, Benary Manuela, Axmann Ilka, Steuer Ralf, 2013, How cyanobacteria pose new problems to old methods: challenges in microarray time series analysis. BMC Bioinformatics, 14, 133 (full text)
Westermark Pål O, Herzel Hanspeter, 2013, Mechanism for 12 hr rhythm generation by the circadian clock. Cell Rep, 3, 1228-38 (full text)
Kuokkanen Paula T, Ashida Go, Carr Catherine E, Wagner Hermann, Kempter Richard, 2013, Linear summation in the barn owl's brainstem underlies responses to interaural time differences. J. Neurophysiol., 110, 117-30 (full text)
Granada Adrián E, Bordyugov Grigory, Kramer Achim, Herzel Hanspeter, 2013, Human chronotypes from a theoretical perspective. PLoS ONE, 8, e59464 (full text)
Hertel Stefanie, Brettschneider Christian, Axmann Ilka M, 2013, Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock. PLoS Comput. Biol., 9, e1002966 (full text)
Wiegard Anika, Dörrich Anja K, Deinzer Hans-Tobias, Beck Christian, Wilde Annegret, Holtzendorff Julia, Axmann Ilka M, 2013, Biochemical analysis of three putative KaiC clock proteins from Synechocystis sp. PCC 6803 suggests their functional divergence. Microbiology (Reading, Engl.), 159, 948-58 (full text)
Pangalos Maria, Donoso José R, Winterer Jochen, Zivkovic Aleksandar R, Kempter Richard, Maier Nikolaus, Schmitz Dietmar, 2013, Recruitment of oriens-lacunosum-moleculare interneurons during hippocampal ripples. Proc. Natl. Acad. Sci. U.S.A., 110, 4398-403 (full text)
Bossan Benjamin, Hammerstein Peter, Koehncke Arnulf, 2013, We were all young once: an intragenomic perspective on parent-offspring conflict. Proc. Biol. Sci., 280, 20122637 (full text)
Blüthgen Nils, Legewie Stefan, 2013, Robustness of signal transduction pathways. Cell. Mol. Life Sci., 70, 2259-69 (full text)