members:upadhyay:start

Education & Research experiences
Postdoctoral fellow (Developmental Chronobiology) @ Friedrich Miescher Institute (FMI), Basel, SWITZERLAND

Ph.D (Chronobiology, Molecular Systems Biology) 2016-20
cumulative thesis: “Molecular switches facilitate rhythms in the circadian clock of Neurospora crassa in supervision @ Charite & Humboldt University of Berlin (HU) & co-supervision @ Heidelberg University, GERMANY

Predoctoral fellow (Evolutionary Biology) @ University of Witwatersrand (Wits), Johannesburg, SOUTH AFRICA

M.Phil (Marine Biology, Proteomics, Climate Change) 2013-15 @ The University of Hong Kong (HKU), HONG KONG

Premasters fellow @Indian Institute of Science (IISc), INDIA

B.Eng (Biotechnology Engineering) 2008-12 , INDIA

“Timing matters !”


[ Seminar of the Hanspeter Herzel Group (Hanspeter_Scholar and Hanspeter_Web). We met every Tuesday at 14:45 in the Haus4 seminar room(s) of the ITB unless stated otherwise. Seminar list was compiled by Abhi (Abhi_Medium) since 05.12.2017 until 30.07.2020]





28.07.2020
Summer vacation

14.07.2020
Christoph
Compensation Mechanisms in the Mammalian Circadian Clock

07.07.2020
Stephanie
East-West Asymmetry in Recovery from Jetlag

30.06.2020
Rebekka
Circadian Rhythms: Data Analysis and Mathematical Modelling

23.06.2020
All
SRBR2020 debriefing

16.06.2020
Maria
Human chronobiology in Sydney

09.06.2020
Bharath
Modeling the cockroach circadian clock

01.06.2020 - 03.06.2020
SRBR 2020
https://srbr.societyconference.com/v2/

26.05.2020
Hanspeter
Q&A session on basics of statistics-II

19.05.2020
Hanspeter
Q&A session on basics of statistics-I

12.05.2020
Hanspeter
The dynamic origin of genomic isochores

05.05.2020
Anna
Peripheral circadian oscillators couple via exchange of paracrine signaling molecules, including TGF-β

28.04.2020
Nora
Inferring signaling pathways activation from circadian time series using PROGENy

21.04.2020
Inge
Nonlinear dynamics in models of the circadian clock

14.04.2020
Abhi
Multiple random phosphorylations provide long delays and switches in Neurospora clock

07.04.2020
Marta
Progress report on anna's manuscript: mechanisms of intercellular coupling among peripheral circadian oscillators

31.03.2020
Everyone
Updates to Hanspeter


Following COVID-19 guidelines we switched to “online virtual meetings (via ITB zulip jitsi and/or Zoom)” while working from home offices since 16.03.2020


10.03.2020
Ecegül
Amplitudes and phases of clock genes in mammalian tissues
Hanspeter
Chronobiology and network theory

25.02.2020
Hanspeter
Brainstorming: Control of circadian phases

11.02.2020
Hanspeter
Strange nonchaotic attractors

04.02.2020
Abhi
1) Introduction to kinetic proofreading (KPR)
2) CK1a role in Neurospora clock

28.01.2020
Christoph
Ending the message: Alternative Polyadenylation in U-2 OS

21.01.2020
Abhi
Perspectives on multisite phosphorylation

14.01.2020
Bharath
Exact Confidence Intervals for Circadian Parameters

07.01.2020
Nora
inferring signaling pathways activity from time-series gene expression data

17.12.2019
discussion regarding GCC meeting March, 2020

10.12.2019
Christoph
New manuscript under prep: clocks in the wild- entrainment and seasonality related

03.12.2019
Andreas (Dresden)
The mathematics of brain tumour invasion and progression

19.11.2019
No meeting
Raghavendra's talk at ITB seminar

12.11.2019
Hanspeter
brainstormings

05.11.2019
Gregor (Heidelberg)
Spatially resolved Wavelet Analysis of SCN slices

29.10.2019
Hanspeter, Christoph & Bharath
PRCs, jet-lag, seasonality: data and models

22.10.2019
Leylanur
Tissue-specific regulation of clock-controlled genes- Learning from MyoD1 in muscle
Abhi
impressions from LASC-2019 Uruguay meeting

15.10.2019
Anna
Potential mechanism of intercellular coupling between peripheral circadian oscillators

24.09.2019
Nikhil
Heritable gene expression variability governs clonal heterogeneity in circadian period

17.09.2019
Anne
Statistical Analysis of Circadian Rhythms in Mice Liver under Different Diets

03.09.2019
Hanspeter
impressions from EBRS, Lyon https://www.ebrs2019.com/

13.08.2019
Sara (Zurich)
The Forebrain Synaptic Transcriptome Is Organized by Clocks, but Its Proteome Is Organized by Sleep

30.07.2019
Literature seminar
everyone

23.07.2019
Gordon and interesting papers/reviews
Gordon Chronobiology 2019 conference impressions

02.07.2019
Muge
Update on master thesis: Time Series Analysis of Circadian Rhythms in Single Cells– Effect of Cell Cycle

18.06.2019
Peter (Newzealand)
Origin of genetic coding and deep phylogeny of aaRS coding enzymes.

28.05.2019
Hanspeter
Lecture: Simulating stochastic oscillations

21.05.2019
Bharath
Analysing circadian datasets at ultradian timescales.

07.05.2019
Christof's lab
Discussion about experimental data and modelling.

30.04.2019
Patrick's PhD defense
Systems level generation of mammalian circadian rhythms and its connection to liver metabolism.

25.04.2019
Patrick's rehearsal
rehearsal on 14:00.

23.04.2019
Claudia (Münster)
The analysis of resource allocation in the genetic material as a tool to link molecular evolution to ecosystems biology.

16.04.2019
Marta
Discussion/presentation about the next projects.

09.04.2019
Abhi
Discussion/presentation about the next projects.

19.03.2019
Brainstorming with Hanspeter
How to write research papers, project thesis.

05.03.2019
Müge
The phase shifting effects of Cisplatin on Single Cell Traces

12.02.2019
Dieter
topic of his interest

05.02.2019
Brainstorming with Hanspeter
Scientific career : goldmine or minefield

29.01.2019
Marta
Ojalvo model: spontaneous synchronization

22.01.2019
Discussion: Hanspeter, Marta and Abhi
Some interesting fundamental biochemical oscillators

15.01.2019
Erich (Muenster)
Brainstorming with Bornberg-Bauer - everybody could present his/her project briefly

08.01.2019
Jan
Bachelors Thesis (Uwe Ohler Group @MDC Berlin): Revealing the regulatory effect of RNA-binding proteins on transcript abundances in single cell studies

Happy New Year 2019

27.11.2018
Janita
Masters rotation: Nonsinusoidal transcription rhythms in the mouse liver

20.11.2018
Discussion: Hanspeter & Christoph
Some interesting fundamental biochemical oscillators

07.11.2018
Dorothee (Bielefeld)
Everyone's brief presentation of their project's state of the art

30.10.2018
All
Literature seminar

23.10.2018
Hanspeter
Lecture: Understanding diffusion, super diffusion and sub diffusion using the Kubo formula

16.10.2018
Hanspeter
Lecture: Time series analysis: ARIMA models

09.10.2018
Pablo (Kassel)
Multi-scale electrical activity in Cockroach circadian clock

08.10.2018
Kwangwon (USA)
Fitness in a microbe: how the circadian clock is shaped by the environment

18.09.2018
Hanspeter
Lecture: Floquet multipliers and intermittency

11.09.2018
Isao (Japan)
Single cell analysis of Arabidopsis circadian clock and its mathematical modeling

04.09.2018
Hanspeter
Lecture: Fractal basin boundaries

31.07.2018 to 28.08.2018
Summer Holidays Intermission
Group meetings would resume from 04.09.2018

17.07.2018
Elmir
Master thesis report: Modelling of gene regulatory network in mammalian circadian clock

10.07.2018
Hanspeter and others
Literature seminar

03.07.2018
Bharath, Patrick, Marta, Abhi and Hanspeter
Impressions from the SRBR Florida, EMBL Heidelberg, Solvay Brussels

26.06.2018
Hanspeter
Impressions from the SRBR Florida conference

19.06.2018
Pietro
Bachelors thesis project: A mathematical model of cannabinoids' kinetics in dairy cow's milk

12.06.2018
Christoph
Dissociation of Bmal1 and Per1 rhythms (results from the work being done in Japan)

29.05.2018
Hanspeter
Lecture: How to write a thesis?

22.05.2018
Anton
Masters thesis project: Emerging properties of systems of oscillators in regard to SCN desynchronization

09.05.2018
Wolfram
Master Thesis (@EBI Cambridge, UK) defense: Gene un-prediction: Developing a new method to identify spurious protein sequences

24.04.2018
Tanmay
Emergence of memory and learning in intra-cellular signaling networks:where reverberations meet Arnold tongue

17.04.2018
General discussions
Papers, meetings feedbacks, next!

03.04.2018
Abhi, Marta
Project's state of the art

27.03.2018
Hanspeter
Lecture: Numerics of Ordinary and Stochastic Differential Equations (ODEs and SDEs)

20.03.2018
Philipp
Defense: Master's Thesis
Patrick
Manuscript discussion

06.03.2018
Elmir
Project: state of the art

20.02.2018
Bharath
Paper: Positive Feedback Promotes Oscillations in Negative Feedback Loops http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104761#abstract0

30.01.2018
Anton
Introduction of himself & recent masters project

23.01.2018
Hanspeter
Lecture: Harmonics and ultradian rhythms

16.01.2018
Christoph
Choroid plexus as an important circadian clock

09.01.2018
Abhi
Paper: DNA Replication Is Required for Circadian Clock Function by Regulating Rhythmic Nucleosome Composition

02.01.2018
New Year 2018 Welcome, Group Meet

19.12.2017
Hanspeter
Lecture: Probability density

12.12.2017
Bharath
Analysis of neuronal spikes data

05.12.2017
Hanspeter
Lecture: Fat Fractals

27.11.2017
Takayuki
TBA

14.11.2017
Abhishek
State of the art of project mathematical modelling of Neurospora circadian clock

07.11.2017
Philipp
Temperature entrainment in Neurospora crassa

24.10.2017
Lars
Predictability of circadian transcripts via ChIP-seq analysis

17.10.2017
Marta
TBA

10.10.2017
Adrian
Circadian Clock & Cell Cycle: Effects on Breast Cancer Radio and Chemotherapy

26.09.2017
Wolfram
Predicting ribosome stalling events and their linkage to protein secondary structure

05.09.2017
Christoph, Hanspeter
Gordon, USA and EBRS, Amsterdam Meetings Reports

29.08.2017
Isao, Bharath, Hanspeter
Gordon Meeting Report https://www.grc.org/chronobiology-conference/2017/

22.08.2017
Abhi (Poster Abstract P142), Marta, Patrick
Gordon and EBRS Meetings Reports http://www.nin-meeting.nl/

11.07.2017
Carl H. Johnson (USA)
Temperature and Metabolic Compensation

07.07.2017
Everyone
Their projects briefly to Carl Johnson

27.06.2017
Carl H. Johnson (USA)
Is the TTFL the Core Circadian Pacemaker? An Alternative Perspective

30.05.2017
Abhishek
Paper: The frequency natural antisense transcript first promotes, then represses, frequency gene expression via facultative heterochromatin

23.05.2017
Sarah
Paper: Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver http://www.cell.com/cell-metabolism/abstract/S1550-41311630534-4

09.05.2017
All
Symposium on Theoretical Chronobiology, Lille, France

18.04.2017
Bharath
Paper: Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology http://www.sciencedirect.com/science/article/pii/S1550413116305356

28.03.2017
Patrick
Snakemake

21.03.2017
Christoph
Quantifying Coupling Strength of Circadian Oscillators

14.03.2017
Patrick
Circadian clock and liver metabolism

07.03.2017
Isao Tokuda, Japan
Variable entrainment property of Arabidopsis circadian clock by collective phase sensitivity

28.02.2017
Abhishek
Neurospora crassa: introduction of its biology, circadian clock & mathematical models

14.02.2017
Layal
RNA-seq data analysis, differential gene expression and alternative splicing

07.02.2017
All
Literature Seminar

31.01.2017
Martin
Circadian activity of two Drosophila species

17.01.2017
All
Literature Seminar

20.12.2016
Jihwan Myung, Taiwan
Philosophizing and Physiologizing on Time and Mood in the Brain

12.12.2016
Hanspeter
Maximum-Entropy Principle

06.12.2016
Hanspeter
Modeling diffusion processes

22.11.2016
All
Literature Seminar

08.11.2016
Matthias
TBA

02.11.2016
Bharath
Analysis of Circadian Cellular Bioluminescence Recordings using a Kalman Smoother

25.10.2016
Sarah
Mitochondrial Network Morphology

18.10.2016
Patrick
Vectorfield Optimization

04.10.2016
Hanspeter, Patrick
Impressions From the ICSB Spain Meeting http://www.crg.eu/sites/default/files/ICSB2016_anuncio%20A4_29-01-2016_0.jpg

27.09.2016
Bharath
Quantifying firing properties of VIP neurons

12.07.2016
Felix
Verteidigung Masterarbeit

28.06.2016
Hanspeter
SRBR USA Summary https://srbr.org/wp-content/uploads/2015/10/SRBR-2016-Program-Book-with-abstracts.pdf

21.06.2016
Abhishek
Masters presentation cum PhD interview